Use of a Shock Tube Platform in the Replication of Blast Lung Injury

War and asymmetrical conflicts are becoming increasingly prevalent in the modern world. Due to improvements conflict medicine, survivable injuries now more severe than they once were. Therefore, it is important ever that there exist scientific engineering methods for replicating wartime context of laboratory. We have developed one such method: a shock tube platform testing ex vivo samples porcine respiratory system. Using this platform, we can, some extent, simulate pathophysiological consequences blast lung. This condition commonly present victims explosive blasts, both those due typical armaments Improvised Explosive Devices (IEDs). Presented here results experiments conducted using bronchiole tissue as organ cultures. Data presented show epithelial damage, consistent with known trauma-induced cell injury can lead acute distress syndrome (ARDS).